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Zambia has demonstrated significant commitment to increasing domestic expenditure on health to ensure sustainable health sector financing. From 2003 to 2014, government health expenditure increased from US$67 million to US$514 million. However, beginning in 2013, the country’s economic growth slowed substantially, from an average of almost 8% annually to 3.4% in 2016. As a result, government revenues fell well below projections. This report, provides findings from an assessment of the health financing landscape in Zambia. It serves as an evidence base for effective engagement and advocacy for increased domestic resource mobilization for health, specifically for HIV, TB, and malaria. The report explores how the health sector is financed, the status of various health financing mechanisms, the potential for increased resource mobilization, potential areas that could be targeted to increase efficiency, and the budget process.